Published by NEJM Journal Watch, November 25, 2015
By Amy Orciari Herman
Roughly a quarter of men who have sex with men (MSM) should receive daily pre-exposure prophylaxis (PrEP) to lower their risk for HIV acquisition, according to a CDC analysis in Vital Signs.
Examining national survey data, researchers found that 25% of MSM without known HIV reported having sex with at least two men in the prior year and having condomless sex or a sexually transmitted infection — thereby meeting behavioral criteria for daily PrEP, according to the CDC's 2014 guidelines. In addition, 19% of adult injection-drug users without HIV reported using a needle that had already been used by another person — making them candidates for daily PrEP. Lastly, 0.4% of heterosexually active, HIV-negative adults should receive PrEP, based on high-risk behaviors such as sex with an HIV-infected person.
The researchers estimate that overall, more than 1.2 million U.S. adults have indications for PrEP. They call for "efforts to increase knowledge of and access" to such treatment.